| Title: | Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease: The BEAMS Randomized Clinical Trial |
Authors: | Ekstrom, Magnus;Ferreira, Diana;Chang, Sungwon;Louw, Sandra;Johnson, Miriam J.;Eckert, Danny J.;Fazekas, Belinda;Clark, Katherine J. ;Agar, Meera R.;Currow, David C.;McDonald, Christine;Miners, John;Kirkpatrick, Carl;Somogyi, Andrew;Denehy, Linda;McCaffrey, Nikki;Lam, Lawrence;Greene, Aine;Le, Brian;Clark, Katherine ;Fong, Kwun;Agar, Meera;Joshi, Rohit;Kilbreath, Sharon;Ferreira, Diana;Clow, Angela;Smith, Nina;Ryan, Richella;Booth, Sara;Martin, Peter;Kanathigoda, Suharsha;Sheehan, Caitlin;Lee, Jessica;Allcroft, Peter;Cameron-Taylor, Erica;Good, Philip;Welch, Louise;Chye, Richard;Phillip, Jennifer;Wheatley, John;krishnan, Anu;Epton, Michael;Aggarwal, Rajesh;McCloud, Philip;Chan, Jessie;Bellamy, Douglas;Bellemore, Frances;Bhatarai, Priyanka;Biggins, Helen;Birch, Mary-Rose;Burke, Lesley;Burns, Tracey;Byfieldt, Naomi;Charlesworth, Diana;Collins, Gillian;Cooper, Helen;Cosic, Urska;Courtney, Deborah;Cupples, Georgie;Dowd, Anna;Dunleavey, Ruth;Edgar, Terence;Fischer, Amanda;Fuhrmeister, Lisa;Gesling, Jan;Hart, Rosetta;Hopkinson, Kim;Kaczurowski, Michelle;Kidd, Sally;Kingi, Ngaire;Margitanovic, Vera;McCarthy, Gillian;O'Reilly, Robin;Perry, Mary;Raymond, Bronwyn;Saward, Di;Shanon-Honson, Aaron;Sullivan, Karyn;Tonkin, Michelle;Vandersman, Zac;West, Penny;Wilcock, Julie;Storer, Malina;Nestor, Sarah;Thristiawati, Safrina;Sidhu, Manraaj;Australian National Palliative Care Clinical Studies Collaborative |
Affiliation: | Northern Sydney Local Health District |
Department: | Supportive and Palliative Care |
Issue Date: | Nov-2022 |
Publication information: | 328(20):2022-2032 |
Journal: | JAMA |
Abstract: | Chronic breathlessness is common in people with chronic obstructive pulmonary disease (COPD). Regular, low-dose, extended-release morphine may relieve breathlessness, but evidence about its efficacy and dosing is needed. |
URI: | https://nslhd.intersearch.com.au/nslhdjspui/handle/1/40516 |
DOI: | 10.1001/jama.2022.20206 |
URL: | https://jamanetwork.com/journals/jama/article-abstract/2798741 |
Type: | Article |
AHT Subjects: | Chronic Obstructive Pulmonary Disease
Morphine |
Keywords: | Aged;Female;Humans;Male;Delayed-Action Preparations;Double-Blind Method;Chronic Disease;Treatment Outcome;Dyspnea;Morphine;Pulmonary Disease, Chronic Obstructive;Respiratory System Agents |
| Appears in Collections: | Research Publications
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